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The risks of conceiving after 40: What women should know

January 13, 2025
Healthcaretoday, Dr Gayathri Mariappa, motherhood, pregnant, pregnancy, conceiving, late pregnancies, down syndrome, obstetric complications, diabetes, obesity, heart disease, maternal age, conceive, Women at 40, late pregnancies, IVF, intrauterine insemination, IUI, Baby,
Healthcaretoday, Dr Gayathri Mariappa, motherhood, pregnant, pregnancy, conceiving, late pregnancies, down syndrome, obstetric complications, diabetes, obesity, heart disease, maternal age, conceive, Women at 40, late pregnancies, IVF, intrauterine insemination, IUI, Baby,
By Dr Gayathri Mariappa,
Consultant Obstetrician,
Gynecologist and Maternal Fetal Specialist,
Sunway Medical Centre Velocity (SMCV) 
 
​​​​​​​Motherhood is a priceless journey, and for many Malaysian women, the decision to embrace it later in life is becoming increasingly common. This shift reflects evolving societal priorities, including career advancement, financial stability, and personal aspirations, alongside factors such as health considerations and even second marriages. Recent data shows that the percentage of Malaysian women giving birth after the age of 35 has risen from 20.8% in 2017 to 23% in 2022, making the country the second highest in South-East Asia for babies born to women of advanced maternal age. 

The financial demands of raising children have also played a role in shaping this trend. According to the Credit Counselling and Debt Management Agency (AKPK), the estimated cost of raising a child from birth through university, can reach as high as RM1.37 million. These realities, coupled with the rising costs of childcare and education, have prompted many women to plan for motherhood later in life, ensuring a more stable and supportive environment for their family.

Understanding late pregnancies
While all pregnancies carry certain risks, women over 40 are at a higher risk for medical and obstetric complications, including chronic conditions like high blood pressure, diabetes, obesity, and heart disease, which can elevate risks for both the mother and baby during pregnancy.

Recent studies show a stronger link between chromosomal abnormalities and potential congenital malformation in children born to women over 40, with the risks continuing to rise as the maternal age increases. 

Apart from pregnancy-related complications, women over 40 may encounter difficulties to conceive naturally. Women are born with a fixed number of eggs in our ovaries, which gradually decreases over time. By the age of 40, both the quantity and quality of eggs decline significantly, making conception more challenging.
​
Medical innovations supporting late pregnancies
The challenges of conceiving and pregnancy after 40 are now addressed with advancements in medical technology and treatments. For women experiencing difficulties conceiving, options such as in vitro fertilization (IVF) have provided a viable solution. IVF involves stimulating the eggs to grow, retrieving them, fertilizing the egg and sperm in a suitable environment, and transferring the embryo back into the womb. The entire process takes about 2 weeks. 
 
Other fertility treatment options include hormonal medications to stimulate egg growth or intrauterine insemination (IUI), although these methods typically have lower success rates compared to IVF. Infertility can stem from both male and female factors, making it important for couples who are trying for a baby to get the partner to undergo sperm test. In cases where sperm quality is suboptimal, IVF is often the most effective approach.
​
Lastly, non-invasive prenatal testing (NIPT), also known as non-invasive chromosomal checking (NICC), is a recommended screening tool for expecting mothers from as early as 10 weeks into the pregnancy. NIPT is a blood-based genetic test that screens for chromosomal abnormalities by analyzing small fragments of fetal DNA circulating in the mother’s blood. This early and precise screening helps expecting parents make informed decisions about their pregnancy and prepares them for any necessary medical care or interventions.

Preparing for a healthy pregnancy
Preconception care and lifestyle changes are essential for every mother-to-be to achieve a healthy pregnancy such as maintaining a healthy lifestyle, including achieving an optimal body mass index (BMI), consuming a balanced diet supplemented with folic acid, engaging in regular exercise, and avoiding harmful habits such as smoking and alcohol consumption.

Pregnant women should be screened during the first trimester within 10-12 weeks, for potential risks such as preeclampsia, cervical insuffiency, gestational diabetes, and undiagnosed medical conditions like kidney disease or heart conditions. Paternal factors, including smoking and body composition, play a crucial role in improving pregnancy and fetal outcomes.

Embracing motherhood on your own terms
Motherhood is a deeply personal decision, whether it happens before or after 40, shaped by individual values, aspirations, and circumstances. With advancement in medical treatments, right support systems, and proactive care, women now have more opportunities than ever to navigate this journey. From advanced screenings to a range of fertility treatments, age is no longer a barrier to achieving healthy pregnancy and thriving motherhood.
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  • IN THE SPOTLIGHT
    • MALAYSIA HEALTH & POLICY NEWS
    • GLOBAL HEALTH NEWS
  • HEALTH CONDITIONS
    • ANTIMICROBIAL RESISTANCE
    • ARTHRITIS
    • ASTHMA
    • BACK PAIN
    • BRAIN DISORDERS
    • BREAST CANCER
    • CANCER
    • CARDIOVASCULAR DISEASE
    • CERVICAL CANCER
    • CORONAVIRUS DISEASE (COVID-19)
    • DEMENTIA
    • DENGUE
    • DENTAL PROBLEMS
    • DIABETES
    • DRUG ABUSE
    • ECZEMA
    • EPILEPSY
    • EYE
    • FIBROIDS
    • GASTROINTESTINAL DISEASES
    • INFLUENZA (FLU)
    • HEADACHES & MIGRAINES
    • HEPATITIS
    • HIV & AIDS
    • JOINT PAIN
    • KIDNEY DISEASE
    • LUNG CANCER
    • LUPUS
    • MELASMA
    • MENTAL HEALTH
    • MOUTH-AND-TEETH
    • OBESITY
    • OSTEOPOROSIS
    • OVARIAN DYSFUNCTION: UNDERSTANDING PREMATURE OVARIAN FAILURE, POLYCYSTIC OVARY DISEASE AND INFERTILITY
    • SEXUAL & REPRODUCTIVE HEALTH
    • SKIN CONDITIONS
    • SLEEP
    • STROKE
  • DISABILITIES & SPECIAL ABILITIES
    • ADHD and ADD
    • AUTISM SPECTRUM DISORDER
    • BLINDNESS & VISION IMPAIRMENT
    • CEREBRAL PALSY
    • DOWN SYNDROME
    • RARE DISEASES
  • NURSING RESOURCES
  • DIGITAL HEALTH
  • HEALTH PRODUCTS & SERVICES
  • RELATIONSHIPS
  • FAMILY HEALTH & PARENTING
  • EMPOWERING WOMEN
  • MEN'S WELLNESS
  • GOLDEN YEARS
  • ACTIVE LIFE HUB
  • NUTRITION
  • COMPLIMENTARY MEDICINE
  • HUMANITARIAN & COMMUNITY HEALTH
  • AMBULANCE AND FIRST AID GUIDE
  • Community clinics/ Klinik Komuniti
  • Government Dental Clinics / Klinik Pergigian Kerajaan
  • ABOUT US